Kev siv tshuaj pleev ib ce

Glabridin (Glycyrrhiza whitening essence PT-40) nkag mus rau hauv daim tawv nqaij thiab tswj kev ua haujlwm siab, ua kom tawv nqaij dawb thiab ua haujlwm zoo tiv thaiv oxidation.

Glabridin tuaj yeem cuam tshuam cov haujlwm ntawm ntau yam enzymes hauv cov txheej txheem ntawm melanin ntau lawm, tshwj xeeb tshaj yog tyrosinase.

Nyob rau tib lub sijhawm, nws muaj lub luag haujlwm ntawm kev tiv thaiv tawv nqaij tawv, tiv thaiv kab mob thiab tiv thaiv kab mob.

Glabridin yog ib qho khoom ua kom tawv nqaij zoo nrog kev ua haujlwm zoo.

Glabridin yog ib qho tshuaj pleev xim dawb uas qhia los ntawm MARUZEN Company hauv Nyij Pooj xyoo 1989.

Tom qab siv ntau xyoo, nws muaj cov txiaj ntsig zoo thiab kev nyab xeeb zoo.

Tam sim no, nws yog lub luag haujlwm tseem ceeb ntawm cov tshuaj pleev ib ce uas muaj qib siab hauv ntiaj teb.

Dhau li ntawm cov tuam txhab tshuaj pleev ib ce hauv Nyiv thiab Kaus Lim Kauslim, Lancome, Dior, SPA thiab Chanel kuj tau siv dav.
Glabridin hauv kev siv tshuaj pleev ib ce: 1. whitening, inhibiting melanin; 2. anti-inflammatory; 3. antioxidant.
Glabridin, hydrophobic tivthaiv ntawm liquorice extract, muaj kev tiv thaiv zoo thiab ua kom tawv nqaij.

Glabridin kuj muaj cov tshuaj tiv thaiv kab mob.

Cov hydrophobic constituents yog Glycyrrhizin thiab lwm yam flavonoids, uas yuav inhibit melanin.

Hauv vivo thiab hauv vitro kev sim tau ua tiav los tshawb xyuas cov nyhuv inhibitory ntawm Glycyrrhizin ntawm melanin ntau lawm.

1.Inhibition ntawm tyrosinase

Tib neeg tyrosinase yog ib qho tseem ceeb enzyme uas tsis tu ncua tsim melanin, tig daim tawv nqaij los yog ob lub qhov muag ntawm xim av mus rau dub. Peb paub tias cov tawv nqaij raug ultraviolet lub teeb tuaj yeem ua rau qee qhov tshwm sim (xws li mob). Vim tias cov phospholipid daim nyias nyias ntawm daim tawv nqaij raug rhuav tshem los ntawm cov pa oxygen reactive (ROS) raug cuam tshuam los ntawm lub teeb ultraviolet, qhov kev hloov pauv histological no tshwm sim los ntawm erythema thiab pigmentation. Reactive oxygen hom (ROS) yog cov khoom uas ua rau cov tawv nqaij pigmentation, yog li inhibiting nws cov khoom yuav inhibit zus tau tej cov melanin. Glycyrrhizin yog qhov kim tshaj plaws thiab muaj txiaj ntsig zoo ntawm cov khoom xyaw whitening. Raws li cov tshuaj suav tshuaj ntsuab, cov nyhuv whitening ntawm Glycyrrhizin yog 232 npaug siab dua li cov vitamin C zoo tib yam, 16 npaug siab dua li ntawm hydroquinone, txog 13 npaug siab dua li ntawm hydroquinone, thiab 1164 npaug siab dua li ntawm arbutin. Yog li Glycyrrhizin hu ua "whitening gold".

2.Anti-inflammatory nyhuv

Kev tiv thaiv kev ua haujlwm ntawm Glycyrrhizin tau txheeb xyuas los ntawm kev sim. Cov pigmentation tau tshwm sim los ntawm ultraviolet irradiation hauv guinea npua. Tom qab ntawd nws tau smeared nrog 0.5% Glycyrrhizin tov. Nws tau pom tias Glycyrrhizin alleviated daim tawv nqaij mob tshwm sim los ntawm ultraviolet stimulation. Tus nqi yog siv los sawv cev erythema ntawm daim tawv nqaij. Cov qib ntawm qhov mob nyem tuaj yeem suav los ntawm kev sau cov nqi ntawm Glycyrrhizin ua ntej, tom qab thiab tom qab irradiation. Cov nyhuv inhibitory ntawm Glycyrrhizin ntawm kev ua haujlwm cyclooxygenase tau kawm. Cyclooxygenase yog ib qho enzyme uas hloov arachidonic acid mus rau hauv prostaglandins, uas yog cov inflammatory yam. Piv nrog rau pawg tswj hwm (siv tam sim no cyclooxygenase inhibitor, indomethacin), Glycyrrhizin tuaj yeem cuam tshuam kev ua haujlwm ntawm cyclooxygenase. Nws ntseeg tau tias Glycyrrhizin tuaj yeem txo qhov mob los ntawm inhibiting zus tau tej cov arachidonic acid los ntawm inhibiting cyclooxygenase.

3.Antioxidant nyhuv

Glycyrrhizin muaj zog dawb radical scavenging nyhuv. Vitamin C, vitamin E thiab beta-carotene tau lees paub tias yog peb tus huab tais loj antioxidant thiab tiv thaiv kev laus. Glycyrrhizin muaj tib lub peev xwm los tiv thaiv kev laus li vitamin E thiab yog ib qho antioxidant ntuj. Nws tau tshaj tawm tias cov nyhuv antioxidant ntawm Glycyrrhizin yog qhov zoo dua li BHA thiab BHT. [3] Nws tau raug tshaj tawm tias Glycyrrhiza uralensis tuaj yeem siv los txo cov corticosteroids hauv cov kab mob dermatoses thiab txhim kho cov nyhuv steroid.